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Molecular Force Microscopy: New Tool For Measuring Cellular Forces

The goal of mechanobiology is to develop a mechanical description of cells and their parts. Platelet clotting, for example, is an important biological process that can only be fully understood if a mechanical account of platelet dynamics is given. Typically, the first task when setting up a mechanics problem is to create a force diagram – a diagram of the magnitude and direction of all forces involved in a system. One challenge in mechanobiology, however, is that no current technique can construct a force diagram for molecular forces in cells.

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