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Using an IR sensor, researchers have analyzed which active agents affect protein structure and how long the effect lasts. The method they used could one day be applied to the quick and targeted development of drugs with fewer side effects.
Developed by researchers from Ruhr University Bochum in Germany, the new method provides information on structural changes to target proteins within minutes and can help narrow down the type of structural change.
“The way an active agent affects the structure of its target protein has so far been analyzed using time-consuming and material-intensive methods, which may provide extremely detailed spatial information, but which don’t yield results until weeks or even months later,” said researcher Jörn Güldenhaupt.
